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FormularyDecisions Connection Newsletter

Browse new features, discover platform releases, learn about upcoming events, and stay up to date on all the latest insights.

In this month's newsletter ..

 

August is Psoriasis Awareness Month

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The prevalence of psoriasis among US adults aged 20 years or older is approximately 0.3% (7.5 million adults).1 There are 16 biologics2 currently available for the treatment of psoriasis and/or psoriatic arthritis, 2 of which were selected for the first round of price negotiations as part of the Inflation Reduction Act (IRA).3 

Due to the increase in the number and cost of these specialty medications, it is important for healthcare decision makers to have relevant and timely product information to manage costs while still facilitating medication access to patients.  

FD Payers

Check out the Biosimilar Hub to view the current pipeline and market landscape for psoriasis and psoriatic arthritis products. Easily look up phases and launch dates for each product on the landscape overview. 

Reference available Product Snapshots on products for psoriasis. Product Snapshots, curated by clinical pharmacists at ForHealth Consulting team at UMass Chan Medical School, not only provide a high-level overview of the product, but they also include a summary of key clinical trials and Pharmacy & Therapeutics considerations. 

Leverage the Metasearch Results across different psoriasis disease and product pages where you can find a number of articles from credible resources and publications such as PubMed, Journal of Managed Care & Specialty Pharmacy, Pharmacist’s Letter, and more. 

While the Metasearch Results provides an extensive catalog of articles, here is a sample list of articles available on the psoriasis disease page: 

 

 

HCDM

This announcement is an advertisement paid for by IntraBio. FormularyDecisions is not providing a product recommendation. Readers should review all available materials related to the product and indication discussed herein before making any decision related to the purchase or use of the product. Any questions about such products must be directed to the biopharma company. The availability of this product information follows the guidance outlined in the Pre-approval Information Exchange Act of 2022 (Section 810 of H.R. 7667).  

 

 

 

Connecting at conferences

Cencora team members have been busy this summer, attending Advanced Topics for Oncology Pharmacy Professionals (ATOPP) Summit in St. Louis and ThoughtSpot 2024 in Orlando. 

ATOPP Summit

At ATOPP Summit, we connected with oncology and hematology professionals in a collaborative effort to learn about and help address barriers to patient access.

Based on our conversations with attendees, additional resources will be added to the Cell & Gene Therapy Hub on FormularyDecisions as we continue to evolve the tool to meet the product information needs of healthcare decision makers.

FD Payer

Cencora team members from left to right: Molly Bray, MBA; Savannah Scary; Ben Pennell, PharmD, MS; Chara Reed, PharmD; Lakesha Farmer, PharmD, MBA; Cynthia Thai, PharmD

ThoughtSpot 2024

At ThoughtSpot 2024, Tasmina Hydery, PharmD, MBA, BCGP, and Nick Howard, PharmD, presented a continuing education session titled “Old Bugs, New Tricks: The Latest on Vaccines, Immunization Schedules, and Community Health.” ThoughtSpot is an annual conference and trade show organized by Good Neighbor Pharmacy and Cencora, catering to independent community pharmacies and long-term care pharmacies.  

The session covered new prevention methods and pipeline agents, recent guideline updates, vaccine administration practices, strategies for integrating vaccine education within community pharmacies, and the role of community pharmacists in addressing health inequities. It also highlighted how community pharmacists continue to play a crucial part in advancing public health through vaccination by implementing best practices for vaccine education and tackling health disparities within their communities. 
 
FD payers

Cencora team members from left to right: Tasmina Hydery, PharmD, MBA, BCGP and Nick Howard, PharmD 
 

New and updated eDossiers

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Did you know that the eDossier PDF viewer includes a user-friendly table of contents for seamless navigation, as well as tools for annotation that are included in eDossier exports? Explore all these features and more in this 2-minute video tutorial.  

Leverage the innovative tools from the video tutorial to help you navigate eDossiers like a pro. See below for links to the product pages with eDossiers that were posted or updated within the last 90 days. On any product page, you have the option to access the specific eDossiers by submitting an eRequest.

Log into FormularyDecisions today to view all eDossiers available.  

 

Product name
FDA approval date*
FDA-approved indicationc 

BAVENCIO® (avelumab)4

09/06/2023

MCC, RCC, UC

CREON® (pancrelipase)5

04/30/2009

Exocrine pancreatic insufficiency

DAYBUE™ (trofinetide)6

03/10/2023

Rett syndrome

DAYVIGO™ (Lemborexant)7

12/23/2019

Insomnia

ELEVIDYS (delandistrogene moxeparvovec-rokl)8

06/20/2024

DMDd

ELFABRIO® (pegunigalsidase alfa-iwxj)9

05/09/2023

Fabry disease

EOVIST® (gadoxetate disodium)10

07/03/2008

Contrast agent for use with MRI

GADAVIST® (gadobutrol)11

07/12/2019

Contrast agent for use with MRI

IMBRUVICA® (ibrutinib)12

04/21/2020

MCL,d CLL, SLL, WM, MZL,d cGVHD

KEVZARA® (sarilumab)13

06/10/2024

RA, PMR, pJIA

KEYTRUDA® (pembrolizumab)14

06/17/2024

Melanoma, NSCLC, HNSCC, cHL,d PMBCL,d urothelial cancer, MSI-H or dMMR, CRC, gastric cancer, esophageal cancer, cervical cancer, HCC, BTC, MCC, RCC, endometrial carcinoma, TMB-H cancer, cSCC, TNBC

MAVYRET® (glecaprevir/pibrentasvir)15

08/03/2017

HCV

NEXLETOL® (bempedoic acid)16and NEXLIZET® (bempedoic acid and ezetimibe)17

03/22/2024

Hyperlipidemia

OGSIVEO® (nirogacestat)18

11/27/2023

Desmoid tumors

PADCEV® (enfortumab vedotin-ejfv)19

12/15/2023

la/mUC

PAXLOVID™ (nirmatrelvir/ritonavir)20

05/25/2023

COVID-19

PENBRAYA™(meningococcal ACWY polysaccharide, tetanus toxoid conjugate, and bivalent recombinant meningococcal serogroup B vaccine)21

10/20/2023

Meningococcal disease

REZDIFFRA™ (resmetirom)22

03/14/2024

NASHd

STELARA® (ustekinumab)23

07/29/2022

PsO, PsA, CD, UC

TEPMETKO™ (tepotinib)24

02/15/2024

NSCLC

TIVDAK® (tisotumab vedotin-tftv)25

04/29/2024

Cervical cancer

TURALIO® (pexidartinib)26

08/02/2019

TGCT

VALTOCO® (diazepam nasal spray)27

01/10/2020

epilepsy

VANFLYTA® (quizartinib dihydrochloride)28

07/20/2023

AML

VERQUVO® (vericiguat)29

01/19/2021

HF

Vibrant Capsule30

08/26/2022

CIC

WINREVAIR™ (sotatercept-csrk)31

03/26/2024

PAH (WHO Group 1)


*For multi-indication products, the FDA-approved date for the most recent approved indication is listed. 

Key: AML – acute myeloid leukemia; BTC – biliary tract cancer; CD – Crohn’s disease; cGVHD – chronic graft versus host disease; cHL – classical Hodgkin lymphoma; CIC: chronic idiopathic constipation; CLL – chronic lymphocytic leukemia; CRC – colorectal cancer; cSCC – cutaneous squamous cell carcinoma; DMD – Duchenne muscular dystrophy; dMMR –mismatch repair deficient; HAE – hereditary angioedema; HCC – hepatocellular carcinoma; HCV – hepatitis C virus; HF – heart failure; HNSCC – head and neck squamous cell cancer; la/mUC – locally advanced or metastatic urothelial carcinoma; MCC – Merkel cell carcinoma; MCL – mantle cell lymphoma; MRI – magnetic resonance imaging; MSI-H – microsatellite instability-high; MZL – marginal zone lymphoma; NASH – noncirrhotic nonalcoholic steatohepatitis; NSCLC – non-small cell lunch cancer; PAH – pulmonary arterial hypertension; pJIA – polyarticular juvenile idiopathic arthritis; PMBCL – primary mediastinal large B-cell lymphoma; PMR – polymyalgia rheumatica; PsA – psoriatic arthritis; PsO – plaque psoriasis; RA – rheumatoid arthritis; RCC – renal cell carcinoma; SLL – small lymphocytic lymphoma; TGCT – tenosynovial giant cell tumor; TNBC – triple-negative breast cancer; TMB-H – tumor mutational burden-high; UC – ulcerative colitis; WHO – World Health Organization; WM – Waldenström’s macroglobulinemia. 

 

 

 

Upcoming Webinar(s)

AMCP Webinar hosted by FormularyDecisions

Session: Harnessing the Power of AI in Health Evidence Generation Strategy 
Date: Tuesday, Sept 17, 2024 
Time: 2:00-3:00pm ET 

Join this interactive session where we will review insights from healthcare decision makers on AI adoption within their organizations. Additionally, our expert panelists will explore opportunities to mitigate concerns about AI acceptance and hesitation in today’s complex landscape. Using real-world case studies, we will also share how AI can be used to improve efficiencies in aggregating data and communicating evidence. 

Learning objectives: 

  • Review market research insights on AI adoption and perceptions among healthcare decision makers.  
  • Examine current capabilities and limitations of AI-powered tools.  
  • Identify best practices for the practical application of AI in health evidence generation strategy. 
  • Discuss trends and future opportunities to accelerate the trajectory of AI in an evolving landscape.  

Click below for webinar details and to register through the AMCP website
FormularyDecisions-body1-504x504

 

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Learn something new

Equip your clinical team with a resource that streamlines the search for relevant product information. Schedule a demo and ensure your team is leveraging all that FormularyDecisions has to offer.

 

Questions?

We welcome your questions and feedback! Please reach out to the FormularyDecisions team today.
 
References:
1. Armstrong AW, Mehta MD, Schupp CW, Gondo GC, Bell SJ, Griffiths CEM. Psoriasis Prevalence in Adults in the United States. JAMA Dermatol. 2021 Aug 1;157(8):940-946. doi: 10.1001/jamadermatol.2021.2007 
2.National Psoriasis Foundation.  Current biologics on the market. Accessed July 29, 2024. https://www.psoriasis.org/current-biologics-on-the-market/  
3. Juliette Cubanski. KFF.org. FAQs about the Inflation Reduction Act’s Medicare Drug Price Negotiation Program. Published: Jan 31, 2024. Accessed July 29, 2024. https://www.kff.org/medicare/issue-brief/faqs-about-the-inflation-reduction-acts-medicare-drug-price-negotiation-program/  
4. Bavencio prescribing information. EMD Serono, Inc.; 2024. https://www.emdserono.com/us-en/pi/bavencio-pi.pdf  
5. Creon prescribing information. AbbVie Inc.; 2024.  https://www.rxabbvie.com/pdf/creon_PI.pdf  
6. Daybue prescribing information. Acadia Pharmaceuticals Inc.; 2023. https://daybuehcp.com/daybue-pi.pdf   
7. Dayvigo prescribing information. Eisai Inc.; 2023. https://www.eisaipatientsupport.com/-/media/Files/DAYVIGO/PDF/prescribing-information.pdf?hash=b773622b-b11d-419e-9dee-068c55a90aab  
8. Elevidys prescribing information. Sarepta Therapeutics; 2024. https://www.elevidys.com/pi  
9. Elfabrio prescribing information. Chiesi USA, Inc.; 2023. https://resources.chiesiusa.com/Elfabrio/ELFABRIO_PI.pdf  
10. Eovist prescribing information. Bayer HealthCare Pharmaceuticals; 2024. https://labeling.bayerhealthcare.com/html/products/pi/Eovist_PI.pdf   
11. Gadavist prescribing information. Bayer HealthCare Pharmaceuticals; 2024. https://labeling.bayerhealthcare.com/html/products/pi/gadavist_PI.pdf  
12. Imbruvica prescribing information. AbbVie Inc.; 2024. https://www.rxabbvie.com/pdf/imbruvica_pi.pdf  
13. Kevzara prescribing information. sanofi-aventis; 2024. https://products.sanofi.us/kevzara/kevzara.pdf  
14. Keytruda prescribing information. Merck & Co., Inc.; 2024. https://www.merck.com/product/usa/pi_circulars/k/keytruda/keytruda_pi.pdf  
15. Mavyret prescribing information. AbbVie Inc.; 2023. https://www.rxabbvie.com/pdf/mavyret_pi.pdf 
16. Nexletol prescribing information. Esperion Therapeutics; 2024. https://pi.esperion.com/nexletol/nexletol-pi.pdf  
17.Nexlizet prescribing information. Esperion Therapeutics; 2024. https://pi.esperion.com/nexlizet/nexlizet-pi.pdf 
18.Ogsiveo prescribing information. SpringWorks Therapeutics, Inc.; 2024. https://springworkstx.com/wp-content/uploads/2024/04/OGSIVEO-US-Prescribing-Information-04.04.24.pdf 
19. Padcev prescribing information. Astellas Pharma US, Inc.; 2023. https://www.accessdata.fda.gov/drugsatfda_docs/label/2023/761137s019lbl.pdf  
20. Paxlovid prescribing information. Pfizer Inc.; 2023. https://labeling.pfizer.com/ShowLabeling.aspx?id=19599  
21. Penbraya prescribing information. Pfizer Inc.; 2024. https://labeling.pfizer.com/ShowLabeling.aspx?id=19937  
22. Rezdiffra prescribing information. Madrigal Pharmaceuticals, Inc.; 2024. https://www.madrigalpharma.com/wp-content/uploads/2024/03/Prescribing-Information.pdf  
23. Stelara prescribing information. Janssen Biotech, Inc.; 2023. https://www.accessdata.fda.gov/drugsatfda_docs/label/2023/125261s158,761044s009lbl.pdf  
24. Tepmetko prescribing information. EMD Serono, Inc.; 2024. https://www.emdserono.com/us-en/pi/tepmetko-pi.pdf  
25. Tivdak prescribing information. Seagen Inc.; 2024.  https://docs.seagen.com/Tivdak_Full_Ltr_Master.pdf  
26. Turalio prescribing information. Daiichi Sankyo, Inc.; 2023. https://daiichisankyo.us/prescribing-information-portlet/getPIContent?productName=Turalio&inline=true  
27. Valtoco prescribing information. Neurelis, Inc.; 2023. https://www.valtoco.com/sites/default/files/pdf/Prescribing_Information.pdf  
28. prescribing information. Daiichi Sankyo, Inc.; 2024. https://daiichisankyo.us/prescribing-information-portlet/getPIContent?productName=Vanflyta&inline=true  
29. Verquvo prescribing information. Merck & Co., Inc.; 2023. https://www.merck.com/product/usa/pi_circulars/v/verquvo/verquvo_pi.pdf  
30. Vibrant capsule prescribing information. Vibrant Gastro, Inc.; 2023. https://www.vibranthcp.com/wp-content/uploads/ifu-hcp.pdf  
31. Winrevair prescribing information. Merck & Co., Inc.; 2024. https://www.accessdata.fda.gov/drugsatfda_docs/label/2024/761363s000lbl.pdf  

The material is being shared to inform you of the availability of information on FormularyDecisions. In providing this information, FormularyDecisions is not promoting any products mentioned, making claims about risks or benefits, or otherwise recommending any product in general or for any patient or formulary. For complete information about the indications, risks, and benefits of any product, please consult appropriate clinical and safety information, including the complete product label and important safety information. All prescribing decisions and/or coverage decisions should be made independently by individuals with appropriate experience in reliance on their independent judgement.. 

b FDA-approved orphan-drug designation.

c The products listed are in the clinical evaluation stage and have not been approved for use by the FDA. The safety and efficacy of these products have not been established. FormularyDecisions is providing this information to alert you to the status of this product and is not promoting this product generally or otherwise recommending this product for use in the treatment of any disease or inclusion on any formulary for which it has not yet been approved.

d FDA-Accelerated Approval pathway
 
FormularyDecisions is owned and operated by Xcenda L.L.C., which is a subsidiary of Cencora, a global pharmaceutical sourcing and distribution services company.
 
The contents of this communication are non-promotional and intended exclusively for healthcare decision-makers, formulary committees, and other similar entities responsible for selecting healthcare products for coverage or reimbursement. FormularyDecisions strongly encourages our members to review all available information about a particular product, including but not limited to the product label, and to rely on their experience and expertise in making decisions about coverage or prescribing.